Home Health SGPT Test: A Comprehensive Guide

SGPT Test: A Comprehensive Guide

by Ezra Luca

When it comes to laboratory studies for diagnosing medical conditions, SGPT test is a significant method for determining liver function. Also known as Alanine Aminotransferase, SGPT is a vital enzyme that is used for the diagnosis of liver injury and assessment of liver status. People who have had hepatitis or are worried about their liver health as well as healthcare workers should understand the peculiarities of this test. This article explores the details of SGPT test, the importance, the result, the reference range, and the associated conditions that can influence the results.

What is SGPT Test?

SGPT test – known as Serum Glutamate Pyruvate Transaminase test – is a medical test which aims to determine the amount of the enzyme SGPT present in the blood. SGPT is predominantly located in the liver followed by the heart, kidneys, and muscles. SGPT is a liver enzyme that becomes elevated when the liver cells are damaged or inflamed and thus it is a useful parameter for assessment of the state of the liver function.

Importance of SGPT Test:

The SGPT test is essential in the identification of different liver conditions such as hepatitis, cirrhosis, and fatty liver disease among others. Healthcare providers use SGPT to determine the severity of liver injury and determine the best course of action. However, regular SGPT testing should be performed for those who have liver diseases or are prone to them depending on their lifestyles – such as alcohol consumption, obesity, or medications.

Interpreting SGPT Levels:

Normal SGPT levels are between 7 -56 units per litres but this may vary from one laboratory to another. High SGPT values suggest liver injury or inflammation but this does not show a direct relationship to the level of hepatic pathology. Imaging studies or liver biopsies may be required to identify the underlying cause and severity of liver disease.

Factors Affecting SGPT Levels:

Several factors can influence SGPT levels, making interpretation challenging without considering the broader clinical context. Common factors affecting SGPT levels include:

  1. Liver Conditions: Hepatitis, cirrhosis or fatty liver disease are some of the major liver disorders which are likely to cause a high level of SGPT.
  2. Alcohol Consumption: High amounts of alcohol consumption cause liver cell damage resulting to high SGPT concentrations.
  3. Medications: Some drugs such as statins, antibiotics and pain relievers can lead to drug-induced liver injury which may result in high SGPT levels.
  4. Obesity: One of the risk factors is increased levels of SGPT as observed in obese adolescents with the fatty liver disease.
  5. Infections: Hepatitis A, B, and C are some examples of viral infections that result in inflammation of the liver and increased SGPT levels.

SGPT Test Procedure:

SGPT test is a blood test that is conducted in a clinical laboratory. A healthcare provider or phlebotomist will apply an antiseptic to the area such as the inside of the elbow or back of the hand before pricking a vein to gather the blood sample. The sample is then submitted to a laboratory for analysis and the results are usually ready in a few days.

Preparing for an SGPT Test:

There are not any special requirements before an SGPT test; it is important to tell the healthcare provider about any medications, supplements, or an illness recently. There is no required fasting unless your doctor asks for it.


The SGPT test is an important indicator of liver functions and can help in the identification of patients suffering from liver diseases. It is therefore important to understand what it represents, how it should be interpreted, which factors influence its levels, from the perspective of either a healthcare professional or a person concerned about healthy liver. Timely evaluation of SGPT as a part of liver function tests can help in the prevention and treatment of liver diseases and can lead to a better course of liver diseases.

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